BMC Genomics - Volume 11, issue Preprint

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Electronic ISSN
1471-2164

Abstract

Background

High-throughput genomics has enabled the global mapping of genetic interactions based on the phenotypic impact of combinatorial genetic perturbations. An important next step is to understand how these networks are dynamically remodelled in response to environmental stimuli. Here, we rep

Journal: BMC Genomics, vol. 11, no. Preprint, 2010

Abstract

Background

Aggression is a near-universal behaviour with substantial influence on and implications for human and animal social systems. The neurophysiological basis of aggression is, however, poorly understood in all species and approaches adopted to study this complex behaviour have often been ov

Journal: BMC Genomics, vol. 11, no. Preprint, 2010

Abstract

Background

Intracranial pediatric germ cell tumors (GCTs) are rare and heterogeneous neoplasms and vary in histological differentiation, prognosis and clinical behavior. Germinoma and mature teratoma are GCTs that have a good prognosis, while other types of GCTs, termed nongerminomatous malignant

Journal: BMC Genomics, vol. 11, no. Preprint, 2010

Abstract

Background

Despite vaccination since the 1950s, pertussis has persisted and resurged. It remains a major cause of infant death worldwide and is the most prevalent vaccine-preventable disease in developed countries. The resurgence of pertussis has been associated with the expansion of Bordetella

Journal: BMC Genomics, vol. 11, no. Preprint, 2010

Abstract

Background

The Multinational Brassica rapa Genome Sequencing Project (BrGSP) has developed valuable genomic resources, including BAC libraries, BAC-end sequences, genetic and physical maps, and seed BAC sequences for Brassica rapa. An integrated linkage map between the amphidiploid <

Journal: BMC Genomics, vol. 11, no. Preprint, 2010

Abstract

Background

Genetic linkage maps are essential tools when searching for quantitative trait loci (QTL). To maximize genome coverage and provide an evenly spaced marker distribution a combination of different types of genetic marker are sometimes used. In this study we created linkage maps of four ze

Journal: BMC Genomics, vol. 11, no. Preprint, 2010

Abstract

Background

Anamika et al[1] recently published in this journal a sequence alignment analysis of protein kinases encoded by the chimpanzee genome in comparison to those in the human genome. From this analysis they concluded that several chimpanzee kinases have unusual domain arrangements.

Journal: BMC Genomics, vol. 11, no. Preprint, 2010

Abstract

Background

AFLP markers are widely used in evolutionary genetics and ecology. However the frequent occurrence of non-homologous co-migrating fragments (homoplasy) both at the intra- and inter-individual levels in AFLP data sets is known to skew key parameters in population genetics. Geneticists ca

Journal: BMC Genomics, vol. 11, no. Preprint, 2010

Abstract

Background

To understand gene expression networks leading to functional properties of the soybean seed, we have undertaken a detailed examination of soybean seed development during the stages of major accumulation of oils, proteins, and starches, as well as the desiccating and mature stages, using

Journal: BMC Genomics, vol. 11, no. Preprint, 2010

Abstract

Background

Microsatellites are markers of choice in population genetics and genomics, as they provide useful insight into patterns and processes as diverse as genome evolutionary dynamics and demographic processes. The acquisition of microsatellites through multiplex-enriched libraries and 454 GS-

Journal: BMC Genomics, vol. 11, no. Preprint, 2010