BMC Bioinformatics - Volume 11, issue Suppl 1

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Electronic ISSN
1471-2105

Abstract

Background

Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with these Synthases is not properly understood. Moreover, currently no crystal structure of complexes bou

Journal: BMC Bioinformatics, vol. 11, no. Suppl 1, 2010

Abstract

Background

Several diseases, many of which nowadays pandemic, consist of multifactorial pathologies. Paradigmatic examples come from the immune response to pathogens, in which cases the effects of different infections combine together, yielding complex mutual feedback, often a positive one that bo

Journal: BMC Bioinformatics, vol. 11, no. Suppl 1, 2010

Abstract

Background

Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among species. While previous works in the field performed genomic comparisons and evolutionary studies that were based on specific

Journal: BMC Bioinformatics, vol. 11, no. Suppl 1, 2010